OUR SERVICESMolecular ID-Infectious Pathogens

Detection of Respiratory Tract Infections More Effective with Molecular Testing

Acute respiratory tract infections (ARTIs) such as bronchitis, sinusitis, and rhinitis account for almost 10% of ambulatory care visits in the United States.1 Despite having similar symptoms, upper and lower respiratory tract infections are caused by a wide range of microbes, including RNA and DNA viruses, bacteria, and fungi. However, detection of these pathogens can often be difficult. Immunoassays are limited to a small number of respiratory pathogens and lack sensitivity. While molecular detection is more sensitive, most commercially available tests are expensive, primarily focus on either viruses or bacteria, and lack the flexibility to customize target lists based on laboratory needs. In addition, concurrent prevalence of viral and bacterial pathogens is a growing concern and needs effective detection methods.

AIM Labs’ Solution for Respiratory Tract Infections

AIM Laboratories uses the TheromoFisher OpenArray-TaqMan-based platform to detect respiratory pathogens, including viruses, bacteria and fugal species (See the complete panel). This is a sensitive, syndromic panel–based, real-time PCR solution for the detection of respiratory pathogens. Our platform features the most pathogenic organism targets of any test on the market, including SARS-CoV-2 (COVID-19):

  • Provides simultaneous detection – probable respiratory pathogens as well as antibiotic resistance genes using a single sample, saving time and cost for treatment.
  • Extensive coverage including SARS-CoV-2 targets – the largest number respiratory pathogen targets of any respiratory test on the market.
  • Multiple sample input types – including nasopharyngeal (NP) swabs, bronchoalveolar lavage (BAL), and nasal aspirate.
  • Turnaround time – Typically 24 hours after receiving the sample.
Respiratory Tract infection (RTI) Panel
Adenovirus 1
Adenovirus 2
Human Bocavirus
Human Coronavirus 229E, HKU1, NL63, OC43, MERS-CoV, SARS-CoV-1 and SARS-CoV-2
Human herpesvirus 5 (HHV5 – Cytomegalovirus)
Human Enterovirus (pan assay)
Human Enterovirus D68
Human herpesvirus 4 (HHV4 – Epstein-Barr Virus), HHV3 (Varicella zoster Virus), HHV5 and HHV6
Human Rhinovirus 1, and 2
Influenza A/H1-2009
Influenza A/H3
Influenza B
Measles virus
Mumps virus
Human Parainfluenza virus 1, 2, 3 and 4
Human parechovirus

Human Metapneumovirus (hMPV)

Pneumocystis jirovecii
Human Respiratory Syncytial Virus A (RSVA) and RSVB
Bordetella bronchiseptica / parapertussis / pertussis
Bordetella pertussis
Bordetella holmesii
Chlamydophila pneumoniae
Coxiella burnetii
Haemophilus influenzae
Klebsiella pneumoniae
Legionella pneumophila
Moraxella catarrhalis
Mycoplasma pneumoniae
Staphylococcus aureus
Streptococcus pneumoniae
Streptococcus pyogenes

Did You Know?

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Each year, it is estimated that more than 177,000 older adults are hospitalized and 14,000 of them die in the United States due to RT infections.

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What are the common symptoms of a UTI?

UTIs can present with different symptoms for different people. Some of the more common symptoms that may indicate you may have a UTI include

  • A strong and frequent urge to urinate
  • A burning sensation when urinating
  • Strong smelling urine
  • Blood in the urine
  • Cloudy urine
  • Pain in the lower abdomen
What is the common cause of a UTI?
    1. The most frequent cause of a UTI is the bacteria Escherichia coli (E. coli), which is typically found in the colon. However, sometimes other bacteria are responsible.
    2. UTIs can also be caused by an infection in the urethra. This can occur when GI bacteria spread from the anus to the urethra.
What are risk factors for developing a UTI?
    1. Women are at higher risk for developing a UTI. Risk factors for women include:
      • Age: The risk of UTIs increase with age
      • Incomplete bladder emptying
      • Sexual activity
      • Certain forms of contraceptives such as diaphragms and spermicidal agents
      • Menopause: A decline in estrogen causes changes in the urinary tract
    2. Other risk factors not specific to women include:
      • Abnormalities in the urinary tract: Such as kidney stones or an enlarged prostate
      • Immunosuppression
      • Diabetes
      • Catheter use
      • Recent urinary surgery
What is the most common treatment for a UTI?

UTIs are mainly treated with antibiotics in addition to drinking plenty of liquids, especially water

How can you prevent a UTI?
    1. Drink plenty of water and other liquids
      1. Cranberry juice and blueberry juices are believed to help prevent infection
    2. Intake of probiotics such as yogurt
    3. Regular emptying of the bladder, especially following intercourse
    4. Ensure proper personal hygiene