Urinary Tract Infection

THE PROBLEM:
URINARY TRACT INFECTIONS CAN BE DIFFICULT TO DIAGNOSE AND TREAT

Urinary Tract Infections (UTI) are difficult to diagnose because there are vague symptoms and infections. An inaccurate diagnosis can lead to serious consequences.

In fact, typical urine culture misses up to 75% of all UTI-positive patients.1

Additionally, the introduction of Multi-Drug Resistant Organisms (MDROs), oftentimes referred as antibiotic resistance, has made the treatment of UTIs much more challenging.

According to the Centers for Disease Control, every time someone takes an antibiotic they don’t need (or is not indicated for what actually is infecting the patient), they increase their risk of developing a resistant infection in the future.2 That is why it is critical to correctly and rapidly identify the infecting pathogens and exclude antibiotic resistance.

THE SOLUTION:
AIM LABS PROVIDES MOLECULAR UTI TESTING

AIM’s Real-Time PCR (polymerase chain reaction) for UTI pathogen identification, quantification and detection of antibiotic resistance can help clinicians properly and quickly get patients on the right treatment the first time.

AIM Labs can rapidly detect bacterial and fungal targets, eliminating the need for costly, inaccurate or time consuming follow up testing.

PCR is a molecular technique used at AIM’s state-of-the-art laboratories, and can be used to precisely analyze the genetic material of pathogens. Additionally, PCR is three to five times more sensitive than conventional culture. AIM’s UTI solution is one of the fastest available, reporting both pathogen identification and antibiotic resistance testing results within 12 to 24 hours of receiving the patient’s specimen.

WHO IS AT RISK?
IDENTIFYING HIGH RISK PATIENTS

Women tend to be at a higher risk then men for UTIs. And patients with voiding abnormalities related to diabetes, pregnancy, Neurogenic bladder, prostatic hypertrophy, spinal cord injury, and UT instrumentation (catheter).

Additionally, patients who are experiencing: Pyelonephritis, Abdominal tenderness, Immunosuppressed, Prostatitis, Diabetes, Interstitial Cystitis, Men with UTI, Past urinary culture results were contaminated, Recurrent UTI; persistent or complicated, or those on chronic pain care regimens.

DID YOU KNOW?

UTIs are among the most prevalent communityacquired and hospital- acquired infections, affecting almost 50% of the population at least once in their lifetime.
Up to 60% of women have at least one symptomatic UTI during their lifetime.
Women get UTIs up to 30 times more often than men.

MOLECULAR IS BETTER
URINE CULTURE VS. MOLECULAR DIAGNOSIS

A Loyola study followed 150 patients who were split into 2 groups based on whether they believed they were symptomatic for a UTI. Standard culture detected only 57% of the uropathogens, where the enhanced methodology detected 91%.3

URINE CULTURE

Urine culture misses up to 2/3 of all UTI-positive patients and detects organisms in only 4% of all cases to diagnose prostatitis.

It can take an average of 3 to 5 days for results of a urine culture (fungi can take up to 20 days for results).

Antibiotics can mask positive results.

MOLECULAR DIAGNOSIS

Identifies pathogens NOT detectable by culture.

Biochemical analysis within hours.

Detects antibiotic resistance genes unaffected by concurrent antibiotic use.

Helps stem the rise of multi-drug resistant pathogens.

ABOUT OUR PANEL:
ORGANISMS TESTED AND ANTIBIOTIC RESISTANCE IDENTIFIED

/Yeast Organisms Tested: Enterococcus faecium, Escherichichia coli, Acinetobacter baumanii, Citrobacter freundii, Candida albicans, Enterobacter aerogenes, Candida glabrata, Enterococcus faecalis, Kiebsiella oxytoca, Kiebsiella pneuomiae, Morganella morganii, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus saprophyticus, Streptococcus agalactiae

Antibiotic Classes where Resistance is Identified: Aminoglycosides, Betalactams, Carbapenems, Glycopeptides, Macrolides, Penicillins, Quinolones, Sulfonamides, Tetracyclines, Trimethoprim